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Saint-Gobain TYGON® 2475 High Purity Tubing

2475 High-Purity Tubing PHARMACEUTICAL SYSTEMS High-purity tubing providing a high level of purity not previously available in a clear flexible tubing FeaturesBenefits Exceptionally Low Absorption and Adsorption Compared to Silicone Clear and flexible TYGON 2475 High Purity Tubing is ideally suited for use in many sensitive cell culture and fermentation applications. Low AbsorptionAdsorption Maintaining fluid integrity during transfer is critical in numerous pharmaceutical and biotechnology applications. Loss of fluid through migration into the tubing walls can cause inconsistencies in final product results. TYGON 2475 High Purity Tubing is hydrophobic and will resist the absorptionadsorption of aqueous fluids. This reduction in absorption adsorption minimizes the risk of fluid alteration in single or repeat use applications. Designed for Purity Until now clear flexible tubing was restricted from use in many applications due to concern of plasticizer extraction. TYGON 2475 High Purity Tubing is entirely free of any plasticizers. This unique tubing uses the latest in polymer technology to provide an entirely clear and flexible tubing choice for sensitive fluid transfer applications. Smooth Inner Surface Improves Sanitation Analysis has shown the inner surface of TYGON 2475 High Purity Tubing to be smoother than other frequently specified flexible tubings. This smooth surface inhibits particulate entrapment onto the tubing wall and reduces the potential for bacterial growth and contamination. A smoother fluid path also improves fluid flow characteristics by reducing surface area and lowering adherence of fluid onto the tubing wall. Reduced Disposal Concern TYGON 2475 High Purity Tubing is also unique when it comes to disposal. In todays environment incineration is commonly used to dispose of contaminated materials. Many tubings actually contribute to this problem by releasing hazardous byproducts such as chlorine when burned. TYGON 2475 tubing only releases carbon d

ioxide and water when properly incinerated. Superb Chemical Resistance TYGON 2475 High Purity Tubing is virtually unaffected by chemical sanitizers and cleaners. As a result it can be cleaned repeatedly without decreasing its service life. The non-wettable surface of the product facilitates complete drainage of fluid during the cleaning process. Smooth Inner Surface Inhibits Particulate Entrapment Environmentally Safer to Dispose Reduces Cost of Disposal Highly Resistant to Aggressive Cleaners and Sanitizers Plasticizer Free Meets USP Class VI and FDA Criteria Typical Applications Sterile Filling and Dispensing Systems Diagnostic Equipment Nuclear Equipment Laboratory Analytical Instrumentation Infusion Sets for Parenterals and Drugs Cosmetic Production Food and Beverage Processing Cell and Tissue Culture Transport 2475 High-Purity Tubing TYGON 2475 Manufactured Sizes and Pressures Part Number I.D. O.D. inches inches ACG00003 116 ACG00007 18 ACG00012 316 ACG00017 14 ACG00022 516 ACG00027 38 ACG00038 12 ACG00046 58 ACG00053 34 ACG42064 1 Wall Thickness inches Length feet Minimum Max. Suggested Vacuum Bend Working Rating In. Radius Pressure at of Mercury 73F psi at 73F inches 116 116 116 116 116 116 18 18 18 316 50 50 50 50 50 50 50 50 50 25 18 14 12 34 1-38 1-34 1-12 2-14 3-14 3 316 14 516 38 716 12 34 78 1 1-38 85 50 40 30 18 20 29 25 21 20 29.9 29.9 29.9 29.9 29.9 25.0 29.9 29.9 29.9 29.9 Working pressures are calculated at a 15 ratio relative to burst pressure using ASTM D1599. The values listed for working and burst pressures are derived from tests conducted under controlled laboratory conditions. Many factors will reduce the tubings ability to withstand pressures including temperature chemical attack stress pulsation and the attachment to fittings. It is imperative that the user conduct tests simulating the conditions of the application prior to specifying the tubing for use. Relative Chemical Resistance Properties Tubing TYGON 2475 Fluoroelastome

rs Urethane PVC Thermoplastic Rubber Neoprene Nitrile Rubber Silicone EVA Acids conc. med. weak Bases conc. med. weak Salts F E U F U E E U E F E E U E F E U U E F E F F E E E F F E E E E F E E E F U F F E U U U U U F U U F F U F E E U E E U U F E E F E E E F E E E F E E E F E U U U U Alcohols Ketones TYGON 2475 Typical Physical Properties Property ASTM Method Value or Rating Durometer Hardness Shore A 15 Sec Color D2240-97 72 Clear Tensile Strength psi MPa Ultimate Elongation Tear Resistance lb-finch kNm Specific Gravity Water Absorption 24 hrs. 23C Compression Set Constant Deflection 158F 70C for 22 hrs. Brittleness by Impact Temp. F C Maximum Recommended Operating Temp.F C Low Temp. Flexibility F C D412-97 2000 13.8 D412-97 D1004-93 700 220 39 D792-91 D570-95 0.9 0.01 D395-89 Method B 84 D746-95 -108 -78 125 52 D380-87 -94 -70 Dielectric Strength vmil kVmm D149-93 587 23.1 Tensile Modulus 100 Elongation psi MPa D412-97 350 2.4 Tensile Set D412-97 187 Unless otherwise noted all tests were conducted at room temperature 73F. Values shown were determined on 0.075thick extruded strip or 0.075 thick molded ASTM plaques or molded ASTM durometer buttons. Sterilization of TYGON 2475 Gas Ethylene Oxide. Radiation Radiation up to 2.5 MRad. E Excellent F Fair U Unsatisfactory Comparative AbsorptionAdsorption of TYGON 2475 Tubing vs. Silicone Tubing Percentage of Preservative Remaining Test Methods Used Drug preservatives were analyzed by gas chromatography after 72 hours of contact with each tubing. 100 90 80 70 60 50 40 30 20 10 0 92 89 TYGON 2475 Silicone 98 75 65 37 24 Benzyl Alcohol 0.9 Phenol 0.4 Saint-Gobain Performance Plastics 2664 Gilchrist Road Akron OH 44305 Tel 330 798-9240 Tel 800 798-1554 Fax 330 798-6968 10 Meta-Cresol 0.4 Methyl Paraben 0.14 TYGON TUBING IS NOT INTENDED FOR USE AS AN IMPLANT MATERIAL Leading the way in Critical Fluid Transfer and Containment. TYGON is a registered trademark. IMPORTANT It is the users responsibility to

ensure the suitability and safety of Saint-Gobain Performance Plastics tubing for all intended uses. Laboratory and clinical tests must be conducted in accordance with applicable regulatory requirements in order to determine the safety and effectiveness for use of tubing in any particular application. For a period of 6 months from the date of first sale Saint-Gobain Performance Plastics Corporation warrants this product to be free from defects in materials and workmanship. Our only obligation will be to replace any portion proving defective or at our option to refund the purchase price thereof. User assumes all other risk if any including the risk of injury loss or damage direct or consequential arising out of the use misuse or inability to use this product. THIS WARRANTY IS IN LIEU OF THE WARRANTIES OF MERCHANTABILITY FITNESS FOR PARTICULAR PURPOSE AND ALL OTHER WARRANTIES EXPRESSED OR IMPLIED. No deviation is authorized. Saint-Gobain Performance Plastics Corporation assumes no obligations or liability for any advice furnished by it or for results obtained with respect to those products. All such advice is given and accepted at the buyers risk. FLS-5084A-PDF-0615-SGCS 2015 Saint-Gobain Performance Plastics